Even common pain relievers like aspirin, ibuprofen, and naproxen, known as nonsteroidal anti-inflammatory drugs (NSAIDs), can cause nausea (as well as a risk of erosion of the lining of the stomach and bleeding.)
“In the time that they sit on the surface of the stomach, which is anywhere between a half-hour and an hour, they can cause significant irritation,” says doctor of pharmacy Patrick Meek, associate professor at the Albany College of Pharmacy and Health Sciences. Take them with food to avoid nausea, or look for “enteric-coated” versions that help protect the stomach.
Certain vitamins and supplements should also be taken with food to avoid queasiness. Iron and vitamin C in particular can upset your stomach. “They have a local irritating effect just because of the formulations, but as soon as they pass the stomach, those symptoms tend to subside,” Meek says.